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Page 1
Expanding role of PI5P4Ks in cancer: A promising druggable target.
FEBS Lett. 2022 Jan;596(1):3-16. doi: 10.1002/1873-3468.14237. Epub 2021 Dec 7.
FEBS Lett. 2022.
PMID: 34822164
Free PMC article.
Review.
Enhanced SREBP2-driven cholesterol biosynthesis by PKCλ/ι deficiency in intestinal epithelial cells promotes aggressive serrated tumorigenesis.
Muta Y, Linares JF, Martinez-Ordoñez A, Duran A, Cid-Diaz T, Kinoshita H, Zhang X, Han Q, Nakanishi Y, Nakanishi N, Cordes T, Arora GK, Ruiz-Martinez M, Reina-Campos M, Kasashima H, Yashiro M, Maeda K, Albaladejo-Gonzalez A, Torres-Moreno D, García-Solano J, Conesa-Zamora P, Inghirami G, Metallo CM, Osborne TF, Diaz-Meco MT, Moscat J.
Muta Y, et al. Among authors: arora gk.
Nat Commun. 2023 Dec 13;14(1):8075. doi: 10.1038/s41467-023-43690-5.
Nat Commun. 2023.
PMID: 38092754
Free PMC article.
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PI5P4Ks drive metabolic homeostasis through peroxisome-mitochondria interplay.
Ravi A, Palamiuc L, Loughran RM, Triscott J, Arora GK, Kumar A, Tieu V, Pauli C, Reist M, Lew RJ, Houlihan SL, Fellmann C, Metallo C, Rubin MA, Emerling BM.
Ravi A, et al. Among authors: arora gk.
Dev Cell. 2021 Jun 7;56(11):1661-1676.e10. doi: 10.1016/j.devcel.2021.04.019. Epub 2021 May 12.
Dev Cell. 2021.
PMID: 33984270
Free PMC article.
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PI5P4Kα supports prostate cancer metabolism and exposes a survival vulnerability during androgen receptor inhibition.
Triscott J, Reist M, Küng L, Mosele FC, Lehner M, Gallon J, Ravi A, Arora GK, de Brot S, Lundquist M, Gallart-Ayala H, Ivanisevic J, Piscuoglio S, Cantley LC, Emerling BM, Rubin MA.
Triscott J, et al. Among authors: arora gk.
Sci Adv. 2023 Feb 3;9(5):eade8641. doi: 10.1126/sciadv.ade8641. Epub 2023 Feb 1.
Sci Adv. 2023.
PMID: 36724278
Free PMC article.
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PIP kinases: A versatile family that demands further therapeutic attention.
Llorente A, Arora GK, Grenier SF, Emerling BM.
Llorente A, et al. Among authors: arora gk.
Adv Biol Regul. 2023 Jan;87:100939. doi: 10.1016/j.jbior.2022.100939. Epub 2022 Dec 5.
Adv Biol Regul. 2023.
PMID: 36517396
Free PMC article.
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Cachexia-associated adipose loss induced by tumor-secreted leukemia inhibitory factor is counterbalanced by decreased leptin.
Arora GK, Gupta A, Narayanan S, Guo T, Iyengar P, Infante RE.
Arora GK, et al.
JCI Insight. 2018 Jul 26;3(14):e121221. doi: 10.1172/jci.insight.121221. eCollection 2018 Jul 26.
JCI Insight. 2018.
PMID: 30046014
Free PMC article.
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Temporal control of bidirectional lipid-droplet motion in Drosophila depends on the ratio of kinesin-1 and its co-factor Halo.
Arora GK, Tran SL, Rizzo N, Jain A, Welte MA.
Arora GK, et al.
J Cell Sci. 2016 Apr 1;129(7):1416-28. doi: 10.1242/jcs.183426. Epub 2016 Feb 18.
J Cell Sci. 2016.
PMID: 26906417
Free PMC article.
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